MAMED practical course 2014

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Marine Animal Models in Evolution and Development – MAMED 2014

Focus on Functional Interference

6-16 July 2014, Advanced Training Center, EMBL, Heidelberg, Germany

This 10 day course treats the use of marine animals for research in the fields of Evolution and Development, and will explore how gene function analysis techniques can be applied to non-conventional models.  A broader conceptual background on animal phylogeny and current scientific questions preoccupying the community will also be provided.

Animal models used in the course will include the annelid Platynereis, the crustacean, Parhyale, the cnidarian Clytia, the echinoderm Strongylocentrotus and the acoel Isodiametra.

 A variety of functional interference approaches will be treated from both theoretical and practical points of view: antisense morpholinos, RNA interference, gene editing (Zinc Finger nuclease, TALEN, CRISPR-Cas9), transgenesis, laser ablation and pharmacological approaches.  Participants will gain hands-on experience of a variety of micro-injection methods as well as phenotype analysis by PCR and imaging-based methods.


Preliminary programme
The course programme starts on Sunday 6th July at around 6 pm and finishes on Wednesday 16th July at noon.

MAMED 2014 programme

The course will be held at the Advanced Training Center of EMBL, in Heidelberg (
Participants will be accommodated in double rooms at the nearby ISG Hotel.

Scientific organizers
Maria Ina Arnone (Stazione Zoologica Anton Dohrn, Napoli, IT)
Michalis Averof (CNRS, Institut de Génomique Fonctionnelle de Lyon, FR)
Evelyn Houliston (CNRS/UPMC, Observatoire Oceanologique de Villefranche-sur-mer, FR)
Gáspár Jékely (Max Plank Institute Tübingen, DE)

On-site organiser
Marzia Sidri (EMBL, Heidelberg, DE)

Michael Akam (University of Cambridge, UK)
Detlev Arendt (EMBL, Heidelberg, DE)
Ina Arnone (Stazione Zoologica Anton Dohrn, Naples, IT)
Michalis Averof (CNRS, Institut de Génomique Fonctionnelle de Lyon, FR)
Juliette Azimzadeh (University of Paris Diderot, FR)
Graham Budd (Uppsala University, SE)
Rainer Ebel (Sigma-Aldrich, Taufkirchen, DE)
Anna Gilles (CNRS,Institut de Génomique Fonctionnelle de Lyon, FR)
Andreas Hejnol (Sars, Bergen, NO)
Evelyn Houliston (CNRS/UPMC, Observatoire Oceanologique de Villefranche-sur-mer, FR)
Gáspár Jékely (Max Plank Institute Tübingen, DE)
Peter Lénart  (EMBL, Heidelberg, DE)
Tsuyoshi Momose (Observatoire Oceanologique de Villefranche-sur-mer, FR)
Max Telford (University College London, UK)

How to apply

The course can host a maximum of 16 young researchers (PhD students or post-docs) of any nationality, therefore participation is subject to selection.

To apply please fill in the on-line application form here and submit a motivation letter (max. 1,500 characters including spaces) and your CV to

Applications will be reviewed by the scientific committee and results will be communicated via email by May 20, 2014.

Registration deadline is April 30, 2014

If selected, a participation fee of 1,500 Euros will be waived. This will include all course material, accommodation in double room, meals, transportation from hotel to EMBL and back, paleontological excursion (location tbd).

Please be aware that, as for all Neptune courses, Neptune fellows have priority over external applicants.

This course is sponsored by:

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